Male infertility: Lifestyle factors and holistic, complementary, and alternative therapies. They can be blocked due to various causes, including inadvertent injury from surgery, prior infections, trauma or abnormal development, such as with cystic fibrosis or similar inherited conditions. There are a variety of things that could cause you to experience oligospermia or other sperm disorders. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354694/), Sperm Count and Hypogonadism as Markers of General Male Health, (https://www.sciencedirect.com/science/article/pii/S240545691930210X), (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542010/), (https://www.ncbi.nlm.nih.gov/books/NBK562258/). Hegazy AMS, Mosaed MM, Elshafey SH, Bayomy NA. Though, still, there are no collective systematic or narrative discussion and conclusion of this specific research streak. Sperm quality isnt necessarily something you think about often. Lastly, avoid excessive drug and alcohol use, as well as workout supplements that are known to lower sperm quality. Related: Best home remedies for premature ejaculation. The good news is that having fewer sperm swimming around doesnt mean its impossible to achieve pregnancy it may just make take a bit longer. The authors declare that they have no conflict of interests. Smoking. You may not be able to change some causes of low sperm count, such as one that happens as a result of genetic issues. Urologic surgery. Freezing sperm can be a safe and effective way to preserve your chances of having a biological child. Thats right the main symptom of oligospermia is infertility. There are the gingerols (23-25%) and shogaol (18-25%) in higher quantity compared with others. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. eCollection 2021. Unfortunately, ingesting ginger might cause side effects. Before and after treatment, standardized semen samples were obtained to determine sperm concentration, motility, and SDF according to World Health Organization. Risk factors include having obesity or overweight, having experienced trauma or surgery in or around the testicles, and taking certain medications. While this assisted reproductive technology is the most effective, its also the most invasive and expensive. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. 2020 Feb;52(1):e13487. A typical sperm count is more than 15 million sperm per 1 milliliter of semen. The study was performed in accordance with the Declaration of Helsinki and was approved by the ethical committee of our institute. Fragmented DNA in spermatozoa was visualized by TUNNEL assay using a Cell Death Detection kit (Roche, Mannheim, Germany) according to the manufacturer's instruction. The study medications were prepared in capsules of identical size and appearance and were packaged by the institute pharmacy according to a randomization list. Beyond that, there are various causes of low sperm quality, which can be divided into three main categories: medical, environmental, and lifestyle. This is the first direct demonstration of protective effect of ginger upon sperm DNA integrity in human although such an effect has previously been suggested with the use of other antioxidant (9, 23, 24). Jorsaraei SG, Yousefnia YR, Zainalzadeh M, Moghadamnia AA, Beiky AA, Damavandi MR. Pak J Biol Sci. A low sperm count is also called oligospermia (ol-ih-go-SPUR-me-uh). Evans-Hoecker EA, et al. Other causes may need other treatments. Most common causes behind infertility. 1. Research published in the Journal of Sexual Medicine found that masturbation was common across a mans lifespan. Bethesda, MD 20894, Web Policies Accessibility Sperm count is considered low if it dips below 15 million sperm per milliliter (mL) of semen, although the average is around 75 million sperm per mL. Bordbar H, Esmaeilpour T, Dehghani F, Panjehshahin MR. Stereological study of the effect of ginger's alcoholic extract on the testis in busulfan-induced infertility in rats. The more sperm you have, the better your chances. Front Pharmacol. Keywords: Registration ID in Clinical Trial gov: After treatment, patients showed an average relative reduction of 22.1% in sperm DNA fragmentation (p=0.02) and had 31.3% fewer highly degraded sperm cells (p=0.07). 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event. Many causes are treatable and fertility can be restored. 7th ed. Should I see another type of healthcare provider for additional help? Philadelphia, Pa.: Elsevier 2017. https://www.clinicalkey.com. Solo masturbation was more common than partnered sex during adolescence and in those about 70. Still, the positive effects of ginger on semen quality require additional approval in men. The figure drops slightly to 63.2%, among men in their 30s, and declines with each decade of advancing age. Cigarette smoke contains more than 7000 chemicals and reactive oxygen species (ROS), which impair sperm function, decrease sperm count and ultimately lead to male infertility. Exposure to radiation from X-rays or other sources may harm sperm production as well. The percentage of green fluorescing sperm (TUNEL positive) was determined. Male infertility. People have used ginger for medicinal and culinary purposes for centuries. There are an estimated 180 million couples throughout the world who are dealing with infertility. Learn about the different types of sperm motility and whether Y ("boy") chromosomes actually swim faster than X ("girl") chromosomes. Anawalt BD, et al. Z. officinale crude plant material includes amino acids, raw fiber, ash, protein, phytosterols, vitamins (e.g., nicotinic acid and vitamin A) and minerals. Myths exist about the dangers of regular masturbation. How Do I Choose a Vasectomy Reversal Doctor. However, if your sperm count is low and motility is affected, it could take longer. Influence of ejaculation frequency on seminal parameters. The ginger rhizome (Zingiber officinale L., Family Zingiberaceae) that commonly used as a spice contains several biologically active compounds such as gingerol, shogaols, gingerdiol and gingerdione. The Cardiovascular Benefits and Harms of Ginger | livestrong Causes of a low sperm count In many cases, it's not obvious what causes a low sperm count. The .gov means its official. Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. This study required the enrollment of 45 patients in each group to have at least 80% power to detect effect size of 3 between treatment and placebo groups regard to main outcome (with two-sided test and type 1 error of 5%). (Healthcare providers may call this male infertility or male-factor infertility.) Patients were randomly assigned in two groups, using an interactive voice response system (by phone), based on a computer-generated list of treatment numbers. Although studies are limited and are inconclusive, frequent use of saunas or hot tubs might temporarily impair sperm count. Ali DA, Abdeen AM, Ismail MF, Mostafa MA. An increased level of DNA fragmentation may represent a cause of male infertility and lower natural conception, intrauterine insemination (IUI), and IVF outcome rates (6, 7). Heat-related situations that affect sperm production include: Both prescribed medications and non-prescription substances can make your sperm count low. Federal government websites often end in .gov or .mil. Is our diet killing sperm? Infections like pelvic inflammatory disease can cause severe damage to a woman's reproductive organs and even result in . Men of all age groups reported masturbation in the past month. Here are 10 science-backed ways to increase sperm count and enhance overall fertility in men. Low sperm count. Spending a long time in hot tubs. Only 106 men met the inclusion criteria and were randomly assigned to one of two treatment groups. Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. Activities like heavy drug and alcohol use, as well as using tobacco or vaping, may likewise lower sperm count. Accessed Aug. 8, 2018. We include products we think are useful for our readers. The 8 best foods to boost low testosterone - Medical News Today A systematic review of the effect of oral antioxidants on male infertility. We encourage readers to confirm the information contained herein with other sources and review the information carefully with their professional health care provider. . Stop the use of marijuana and/or other substances. FOIA What Does It Mean If Your Monocyte Levels Are High? Many different tubes carry sperm. Is the ketogenic diet right for autoimmune conditions? Clinical trials and antioxidant outcomes. official website and that any information you provide is encrypted Inadequate sleep makes it difficult to maintain a healthy weight and may lead to obesity. Ginger for Better Sex? Here's What the Science Says - Healthline This was a randomized double-blind, placebo-controlled trial with a 1:1 allocation that performed on 100 candidates who were admitted to Department of Andrology at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, Tehran, Iran for infertility treatment between May 2013 and November 2014. However, the reduction did not cause sperm count to fall below normal thresholds. Here are five things that have been known to cause a low sperm count: Smoking Granted, the amount of cigarettes you would need to smoke a day would have to be nearer to the 20 or so mark in order to affect sperm count. Statistics are hard to come by here, as just how long it takes depends on a number of factors that are individual to you and your partner, including how low your sperm count is and how healthy your sperm are. You can help yourself in all ways, including your sperm count, by adopting a healthy lifestyle in terms of sleep, exercise, diet and alcohol use. Modern research indicates that. ginger; morphology; motility; semen quality; spermatozoon; viability. Low sperm count means that the fluid (semen) you ejaculate during an orgasm contains fewer sperm than normal. At the highest dose (13 mg/kg), sperm count and motility were fourfold less that that observed in controls. Two slides were used for the negative (omitting the enzyme terminal transferase) and positive (using DNase I, 1mg/ml for 20 min at room temperature) controls (22). (2015). Your healthcare provider will take a medical history and do a physical examination. Careers. Andrologia. Having a low sperm count is a significant factor in infertility. In summary, there is solid evidence that ginger enhances semen quality and improves the main sperm parameters such as concentration, viability, motility and morphology. This content does not have an Arabic version. TUNEL assay. Three subjects in the placebo group discontinued treatment because of lost to follow-up. It was also observed that the administration of ginger can significantly increase the testosterone level in plasma and stimulate spermatogenesis (17, 18). A low sperm count may signal other illnesses, but it doesnt mean you wont be able to be a parent. Male reproductive physiology. Research published in the journal Social Psychological and Personality Science found that partners who have sex at least weekly report being happier with their relationships. You may talk to your healthcare provider if youve been deliberately having unprotected sex for a year or even longer. Besides being known as low sperm count, oligospermia is also called oligozoospermia. Infertility is something many men experience. Never disregard professional medical advice or delay seeking it because of something you've read on the Male Fertility & Sexual Health Specialist's web site. By Martin Bastuba, MD, FACS. 2016;18:410. Nonetheless, many men who have a low sperm count are still able to father a child. Here, we systematically review and summarise the current link between ginger and its bioactive compounds with semen quality. Some of these include: Ejaculation problems. Obesity impairs fertility by . Our team thoroughly researches and evaluates the recommendations we make on our site. Some ejaculatory problems can be reversed, while others are permanent. Review/update the Why are sperm counts dropping? Cleveland Clinic is a non-profit academic medical center. In multivariate analysis, SDF was significantly lower in patients receiving ginger compared with placebo (mean difference: 3.21, 95%CI: 0.78-5.63, p=0.009). Increases blood flow. Its important to treat infections promptly. The model included treatment as main effects and age, BMI, pre sperm count, pre sperm concentration, pre sperm motility and pre SDF as covariates. You may be able to reverse the condition if the cause is something you can stop, like taking certain medications or keeping your testicles too warm. Reach and maintain a weight that's healthy for you by exercising and eating a healthy diet. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). As such, you may not see an increase for 3 months, on average. Ejaculation from partnered sex may be particularly beneficial because: Many men also find that ejaculation, whether alone or with a partner, helps them sleep. Men who ejaculate frequently may have a lower risk of prostate cancer, according to a 2016 study that followed men for nearly 2 decades. If youve been having unprotected sex regularly for the last year and havent gotten your partner pregnant, you may want to see your doctor. If there are no sperm at all in the semen sample, the condition is . Oligospermia (Low Sperm Count): Causes & Treatment - Cleveland Clinic (2019). As can be seen, there was no significant difference between two groups at baseline; 53.48 (37.95-69.02) in cases and 56.75 (40.01-73.5) in controls. Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease. How to Increase Sperm Count: 7 Tips for Sperm Health Patients were eligible for enrolment of the study if they were aged more than 45 years old, had idiopathic infertility for more than 2 years, presence of fragmented DNA more than or equal to 15% of ejaculated spermatozoa, absence of leukocytospermia, alcohol or drug addiction, and occupational chemical exposure, not using warfarin or other anticoagulant, not using ginger or other herbal medicines and absence of systemic diseases. There are treatments for many causes of low sperm count. Diagnosis usually involves a physical exam, medical history, and semen analysis. The production of sperm is a complex process and requires normal functioning of the testicles (testes) as well as the hypothalamus and pituitary glands organs in your brain that produce hormones that trigger sperm production. Gholami-Ahangaran M, Karimi-Dehkordi M, Akbari Javar A, Haj Salehi M, Ostadpoor M. Vet Med Sci. Accessed Aug. 29, 2018. You may be surprised to learn that ideal sperm conditions are slightly less than body temperature, which is why the testicles are positioned outside of the abdominal cavity. The author also reviewed two case studies showing that ginger use can cause a drug interaction in people taking blood-thinning drugs like coumadin, and it's . Talk with your healthcare provider and answer all their questions honestly. Clinical management of male infertility. In spite of this animal in vivo and in vitro studies have shown that ginger usage leading to reduced sperm DNA fragmentation, therefore we recommend that a larger randomized, placebo controlled trial on the efficacy and safety of this valuable antioxidant should be done. Its important to note that any treatments or lifestyle changes may not be reflected in your sperm count right away, as the time frame of sperm production and transit is up to 2 to 3 months. What Techniques Can Help a Person Last Longer in Bed? However, if you and your partner want to start or expand your family, the number and quality of swimmers you have may be foremost on your mind. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Related: Babymaking 101: Ways to get pregnant faster. Apoptosis may be also observed in a natural or normal spermatogenesis. Unable to load your collection due to an error, Unable to load your delegates due to an error. Retrograde ejaculation occurs when semen enters the bladder during orgasm instead of emerging out of the tip of the penis. Patients in the treatment group were given a 3-month oral treatment (capsules containing 250 mg of ginger powder twice a day). Infertility among people who have been assigned male at birth contributes to about half of the infertility issues overall. Mayo Clinic; 2019. swelling in the veins that drain the testicles, which is called, issues with erections or ejaculation (For example, diabetes and spinal injuries may cause erectile dysfunction or, conditions like cystic fibrosis or being a genetic carrier of cystic fibrosis may block sperm from entering the semen, medical procedures, treatments, or medications for a range of conditions, including some cancer, antifungal, antibiotic, and ulcer drugs, previous surgery to the male reproductive system, such as testicular surgery, bladder surgery, surgery for undescended testicles, inguinal hernia repair, and of course, a, jobs that require long periods of sitting, such as truck driving, body weight, particularly if you have obesity or overweight, can also affect hormones, swelling or pain in or around the testicles, blood tests to check hormones or chromosomes, ultrasound to visualize the testicles or prostate, biopsy to evaluate sperm production in the case of blockages. In this clinical trial 75 infertile patients were treated by ginger. Sergerie M, Laforest G, Bujan L, Bissonnette F, Bleau G. Sperm DNA fragmentation: threshold value in male fertility. Some of these include: Varicocele. In some cases of abnormal semen quality, your doctor may suggest intrauterine insemination (IUI). 2008 Jul 1;11(13):1723-7. doi: 10.3923/pjbs.2008.1723.1727. Secondary outcomes on bivariate and multivariate analysis, DNA fragmentation between two groups before and after treatment. (2019). Elevated temperatures impair sperm production and function. Average ejaculation frequency varies according to many factors, including a mans: According to the 2015 Sexual Exploration in America Study, partnered sex and the ejaculation that usually accompanies it is most frequent among men ages 2529, with 68.9% reporting vaginal intercourse during the last month. In another study that conducted by Josep Gual-Frau, like our study, SDF decreased after antioxidant usage: Twenty infertile patients with grade I varicocele were given multivitamins (1500 mg L-Carnitine, 60 mg vitamin C, 20 mg coenzyme Q10, 10 mg vitamin E, 200 g vitamin B9, 1 g vitamin B12, 10 mg zinc, 50 g selenium) daily for three months. This study was designed to investigate the effects of ginger (Zingiber officinale) on sperm DNA fragmentation (SDF) in infertile men. An official website of the United States government. Exclusion criteria included: a history of post pubertal mumps, a history of epididymal surgery, a history of radiation therapy or chemotherapy, acute epididymitis, unilateral or bilateral subclinical or recurrent varicoceles and an abnormal hormonal profile. Ginger also contains [6]-gingerol, 8-gingerol, 10-gingerol and 12-gingerol, which have similar anti-oxidate properties (27, 31). Cancer treatments, including chemotherapy, radiation, or surgery, may also affect hormone and sperm production. A spermatocele is a benign, usually painless sac or cyst on the epididymis, which sits above or behind the testicles. Talk to your doctor about medications that can affect sperm count. In fact, you may want to head in for an appointment sooner if you have symptoms like trouble ejaculating, pain in the testicles, or previous surgeries. Dont stop taking prescribed medications on your own without discussing with your healthcare provider. Accessed Aug. 8, 2018. Remedies for Low Sperm Count and Motility - WebMD The effect of Ginger on semen parameters and serum FSH, LH & testosterone of infertile men. Briefly, remaining ejaculated sperm samples were washed from seminal plasma by low-speed centrifugation (600 g; 5 minutes), smeared on microscope slides, air-dried, fixed with 4% paraformaldehyde in phosphate-buffered saline for 60 min, and permeabilized with 0.1% TritonX-100 in 0.1% sodium citrate for 10 minutes at 4oC. Sitting for long periods, wearing tight clothing or working on a laptop computer for long stretches of time also might increase the temperature in your scrotum and slightly reduce sperm production. The researchers remain unsure whether frequent ejaculation fights prostate or any other cancer in men under 40. Male Infertility - Urology Care Foundation http://www.urologyhealth.org/urologic-conditions/male-infertility. Normal spermatogenesis is adjusted appropriately and the balance between cell proliferation continuously and apoptosis (25). Approach to the male with infertility. Most research suggests that frequent ejaculation offers several health benefits. This inconsistency may be attributed to the design of their study. Causes of male infertility: A 9-year prospective monocentre study on 1,737 patients with reduced total sperm counts. 2023 Jan 30;14:1119553. doi: 10.3389/fendo.2023.1119553. This figure of about 50% includes situations where male factor infertility is the only factor and those more common situations where there are fertility factors in both partners. Gual-Frau J, Abad C, Amengual MJ, Hannaoui N, Checa MA, Ribas-Maynou J, et al. Accessed Aug. 8, 2018. FOIA To date, according to the Scopus database, the biological effects of ginger (binominal name: Zingiber officinale), or ginger extracts, and its derived compounds on semen quality and sperm parameters have been revealed in more than 35 original articles. Exposure to environmental toxins can also cause low sperm count. If you don't . Meanwhile, sperm can be collected ahead of time and frozen, or supplied fresh the day of fertilization.
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